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International Journal of Arrhythmia 2017;0(0):
The Impact of the CHA2DS2-VASc Score on Recurrence of Atrial Fibrillation after a Single Catheter Ablation and Atrial Remodeling in Patients with Non-Valvular Atrial Fibrillation
Chan-Hee Lee 1, Sang-Hee Lee 2, Kyu-Hwan Park 1, Dong-Gu Shin 3
1Yeungnam University Hospital, Daegu, Korea
2Pohang Semyeong Christianity Hospital, Pohang, Korea
3Yeungnam Uinversity Medical School, Daegu, Korea
Corresponding Author: Dong-Gu Shin ,Tel: 053-620-3843, Fax: 053-621-3310, Email: dgshin@med.yu.ac.kr
Received: December 30, 2016.  Accepted: February 7, 2017.
Background and Objectives: This study aimed to evaluate the impact of the CHA2DS2-VASc score on the recurrence of atrial fibrillation (AF) after a single catheter ablation procedure in patients with non-valvular AF. We also investigated the relationship between the CHA2DS2-VASc score and atrial substrate.
Subjects and Methods: This study evaluated 151 patients who underwent catheter ablation of non-valvular AF. According to the CHA2DS2-VASc score, the study population was stratified into group 1 (<2, n=72) and group 2 (≥2, n=79). The CHA2DS2-VASc score was analyzed as continuous and categorical values for evaluating its impact on the recurrence of AF after catheter ablation. The left atrial voltage data was analyzed according to the categorical values of this score.
Results: The post-ablation recurrence (31.6% vs. 18.1%, p=0.046) was observed more frequently in group 2. The mean area of the low-voltage zone was 75.64±24.81 cm2 and 94.44±28.09 cm2 in groups 1 and 2, respectively (p=0.005). The left atrial mean voltage in group 2 was 0.99±0.31 mV, and was significantly lower than that (1.49±0.67 mV, p=0.001) in group 1. The CHA2DS2-VASc score was the independent predictor with a modest predictive value for AF recurrence after catheter ablation.
Conclusion: Our study showed that the CHA2DS2-VASc score was associated with atrial remodeling and could be useful to stratify the post-ablation recurrence in patients with non-valvular AF.
Key Words: Atrial Fibrillation ; Catheter Ablation ; Recurrence; CHA2DS2-VASc Score; Atrial Remodeling